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Slc gene family

WebJul 28, 2024 · The solute carrier (SLC) superfamily genes encode more than 300 members that are responsible for the transmembrane transportation of many essential endogenous … WebDec 4, 2024 · There are ~ 430 known transporters in the solute-linked carrier (SLC) gene family, divided into 52 distinct families. Eleven of these gene families contain one or more amino acid transporters. These transporters differ significantly from each other in terms of substrate specificity, ion dependence, and energetics.

Solute Carrier Family - an overview ScienceDirect Topics

WebThe SLC superfamily currently includes 458 transport proteins in 65 families that carry a wide variety of substances across cellular membranes. While members of this superfamily are found throughout cellular organelles, this review focuses on transporters expressed at the plasma membrane. WebApr 19, 2024 · Identification of a Solute Carrier Family-Based Signature for Predicting Overall Survival in Osteosarcoma Identification of a Solute Carrier Family-Based Signature for Predicting Overall Survival in Osteosarcoma Front Genet. 2024 Apr 19;13:849789. doi: 10.3389/fgene.2024.849789. eCollection 2024. Authors Di Zheng 1 , Zhun Wei 1 , Weichun … hazardous removal company reviews https://tipografiaeconomica.net

Solute carrier family - Wikipedia

Web391 rows · The solute carrier (SLC) family is composed of the different transporter families that include ion channels, exchangers, passive transporters (Abbott et al., 2010). There … WebThe SLC8 gene family of sodium-calcium exchangers (NCX) - Structure, function, and regulation in health and disease. Mol Aspects Med. 2013 Apr;34(2-3):220-35. SLC name WebThe SLC (Solute Carrier) series includes the “classical” transporter families (ion-coupled transporters, exchangers, passive transporters, etc.). It contains 65 SLC gene families with 458 different human transporter … hazardous red smoke

Prognostic 7-SLC-Gene Signature Identified via Weighted Gene Co ...

Category:Comprehensive analysis of the SLC16A gene family in pancreatic …

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Slc gene family

Solute Carrier Family - an overview ScienceDirect Topics

WebDec 2, 2024 · Emerging pieces of evidence indicate that the mutation or functional change in the SLC39A family genes leads to the development and progression of multiple … WebApr 1, 2009 · Many of these transporters belong to the solute-carrier (SLC) gene superfamily, and include passive transporters, sym-porters and antiporters, as well as mitochondrial and vesicular transporters. The SLC superfamily comprises 55 gene families, having at least 362 putatively functional protein-coding genes .

Slc gene family

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WebThe overview of human SLC superfamily. The human SLC superfamily comprises 386 member proteins that transport a broad spectrum of substrates, such as nutrients, toxins, … WebThe solute-carrier gene (SLC) superfamily encodes membrane-bound transporters. The SLC superfamily comprises 55 gene families having at least 362 putatively functional protein …

WebJan 15, 2024 · Solute carrier (SLC) family 39 genes encode membrane transport proteins, which control the influx of zinc and may play important roles in human disease including cancer. However, the prognostic value of individual SLC family 39 gene in gastric cancer patients remain unclear. WebApr 30, 2024 · The SLC16A family of monocarboxylate transporters (MCTs) is a subfamily of solute carriers that transport monocarboxylate molecules, including L-lactate and pyruvate, across cell membranes 3....

Websolute carrier family 2, facilitated glucose transporter member 7: SLC2: SLC2A8: SLC2A8: solute carrier family 2, facilitated glucose transporter member 8: SLC2: SLC2A9: SLC2A9: … WebSep 14, 2024 · The solute carrier (SLC) family of proteins is responsible for much of the transport of ions and organic molecules along the renal tubule. In addition, some SLC family proteins mediate housekeeping functions by transporting substrates for metabolism. ... The SLC gene list database was used to generate databases of SLC expression mapped along …

The solute carrier (SLC) group of membrane transport proteins include over 400 members organized into 66 families. Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee (HGNC) and is the … See more By convention of the nomenclature system, members within an individual SLC family have greater than 20-25% sequence identity to each other. In contrast, the homology between SLC families is very low to non-existent. … See more The following families are named under SLC: 1. high-affinity glutamate and neutral amino acid transporter See more Putative SLCs, also called atypical SLCs, are novel, plausible secondary active or facilitative transporter proteins that share ancestral background with the known SLCs. The atypical … See more Most members of the SLC group are located in the cell membrane, but some members are located in mitochondria (the most notable one being SLC family 25) or other intracellular organelles. See more Names of individual SLC members have the following format: where: • SLC is the root name (SoLute Carrier) • n = an integer representing a family (e.g., 1-52) • X = a single letter (A, B, C, ...) denoting a subfamily See more • Outline of families • Datasets and Reagents on the Solute Carrier Family • List of proteins at HGNC website See more

WebNational Center for Biotechnology Information hazardous shipper\\u0027s declaration formWebSLC16A1: familial hyperinsulinemic hypoglycemia type 7 (FHH7) and symptomatic deficiency in lactate transport (SDLT) The SLC16A1 gene is localized at 1p12 and encodes a proton-linked monocarboxylate transporter 1 (MCT1). The transporter is ubiquitously expressed and transports many monocarboxylates, such as lactate and pyruvate, … hazardous safety symbolsWebJun 21, 2024 · Abnormalities in SLC function in the kidney or placenta may be related to the volume abnormalities observed with this disease. For these reasons, this study aimed to investigate whether 263 haplotype tagging single-nucleotide polymorphisms (SNPs) in 26 members of the SLC gene family are associated with preeclampsia in white and black … hazardous shaftWebSolute carrier family. The solute carrier ( SLC) group of membrane transport proteins include over 400 members organized into 66 families. [1] [2] Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee ( HGNC) and is the basis for the ... hazardous shafts specsWebApr 10, 2024 · Interaction among variants in the SLC gene family (SLC6A14, SLC26A9, SLC11A1, and SLC9A3) and CFTR mutations with clinical markers of cystic fibrosis - … hazardous shopWebNov 12, 2008 · We performed a detailed phylogenetic analysis of the entire SLC family and found that 15 of the families place into four large phylogenetic clusters with the largest … hazardous shipping paperworkhttp://slc.bioparadigms.org/ hazardous sign for shipping